Hyuk-Joon Lee Selected Research

spasmolytic polypeptide

1/2020	microRNA-30a arbitrates intestinal-type early gastric carcinogenesis by directly targeting ITGA2.
1/2016	miR-30-HNF4γ and miR-194-NR2F2 regulatory networks contribute to the upregulation of metaplasia markers in the stomach.
11/2012	Proteomic profiling of paraffin-embedded samples identifies metaplasia-specific and early-stage gastric cancer biomarkers.
4/2012	The combined expression of metaplasia biomarkers predicts the prognosis of gastric cancer.
12/2010	Mature chief cells are cryptic progenitors for metaplasia in the stomach.
7/2010	Gene expression profiling of metaplastic lineages identifies CDH17 as a prognostic marker in early stage gastric cancer.
4/2009	Amphiregulin-deficient mice develop spasmolytic polypeptide expressing metaplasia and intestinal metaplasia.

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Hyuk-Joon Lee Research Topics

Disease

150	Stomach Neoplasms (Stomach Cancer) 04/2024 - 04/2003
51	Neoplasms (Cancer) 04/2024 - 04/2003
14	Adenocarcinoma 01/2023 - 02/2006
10	Neoplasm Metastasis (Metastasis) 03/2024 - 04/2012
10	Metaplasia 10/2023 - 04/2009
8	Lymphatic Metastasis 03/2024 - 12/2004
8	Weight Loss (Weight Reduction) 12/2023 - 03/2014
7	Obesity 01/2024 - 11/2009
7	Carcinogenesis 10/2023 - 02/2008
6	Body Weight (Weight, Body) 07/2022 - 03/2014
6	Margins of Excision 01/2019 - 12/2009
4	Carcinoma (Carcinomatosis) 01/2023 - 02/2006
4	Parkinson Disease (Parkinson's Disease) 10/2022 - 11/2017
4	Pain (Aches) 01/2022 - 01/2016
4	Gallstones (Gallstone) 01/2021 - 03/2014
3	Malnutrition (Nutritional Deficiencies) 08/2021 - 12/2011
3	Type 2 Diabetes Mellitus (MODY) 04/2021 - 12/2020
3	Inflammation (Inflammations) 01/2020 - 11/2017
3	Bile Reflux 06/2016 - 06/2008
3	Wounds and Injuries (Trauma) 09/2012 - 09/2009
3	Diabetes Mellitus 08/2012 - 03/2010
2	Flatulence 11/2023 - 12/2019
2	Peptic Esophagitis (Reflux Esophagitis) 01/2023 - 09/2015
2	Morbid Obesity 01/2023 - 07/2017
2	Vomiting 07/2022 - 11/2020
2	Nausea 07/2022 - 11/2020
2	Pathologic Constriction (Stenosis) 01/2021 - 04/2011
2	Diarrhea 01/2021 - 01/2014
2	Synucleinopathies 11/2020 - 11/2017
2	Dumping Syndrome (Syndrome, Dumping) 09/2020 - 06/2016
2	Breast Neoplasms (Breast Cancer) 04/2020 - 07/2002
2	Peritoneal Neoplasms 12/2017 - 02/2012
2	Anemia 05/2017 - 07/2013
2	Infections 01/2017 - 12/2010
2	Liver Diseases (Liver Disease) 06/2011 - 03/2010
1	Wound Infection (Wound Infections) 12/2023
1	Sudden Death 01/2023
1	Adenoma (Adenomas) 01/2023
1	Vitamin B 12 Deficiency (Vitamin B12 Deficiency) 01/2023
1	Intestinal Volvulus (Volvulus) 01/2023
1	Overweight 01/2023
1	Multiple Primary Neoplasms 01/2023

Drug/Important Bio-Agent (IBA)

13	Proteins (Proteins, Gene)FDA Link 01/2023 - 07/2002
11	Biomarkers (Surrogate Marker)IBA 01/2022 - 07/2010
7	spasmolytic polypeptideIBA 01/2020 - 04/2009
5	Indocyanine Green (Cardio-Green)FDA LinkGeneric 02/2022 - 01/2011
4	AlbuminsIBA 01/2023 - 03/2014
4	Hemoglobins (Hemoglobin)IBA 01/2023 - 07/2013
4	alpha-SynucleinIBA 10/2022 - 11/2017
4	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 01/2018
4	Messenger RNA (mRNA)IBA 01/2022 - 03/2005
4	MicroRNAs (MicroRNA)IBA 01/2020 - 04/2009
3	RNA (Ribonucleic Acid)IBA 04/2024 - 01/2023
3	Cadherins (E-Cadherin)IBA 01/2022 - 12/2007
3	Indicators and Reagents (Reagents)IBA 01/2019 - 04/2012
2	Trastuzumab (Herceptin)FDA Link 01/2023 - 08/2021
2	AntralIBA 01/2023 - 02/2010
2	ParaffinIBA 10/2022 - 11/2012
2	Coloring Agents (Dyes)IBA 02/2022 - 01/2011
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 01/2021
2	Analgesics (Analgesic Drugs)IBA 01/2022 - 12/2019
2	Peptides (Polypeptides)IBA 06/2021 - 11/2012
2	Amino Acids FDA Link 01/2021 - 12/2020
2	Serum AlbuminIBA 12/2020 - 11/2017
2	Hormones (Hormone)IBA 09/2020 - 10/2017
2	Carcinoembryonic AntigenIBA 01/2020 - 12/2014
2	CarbohydratesIBA 01/2020 - 12/2014
2	AntigensIBA 01/2020 - 12/2014
2	salicylhydroxamic acid (SHAM)IBA 01/2018 - 01/2016
2	HydrogelsIBA 12/2017 - 02/2012
2	Saline SolutionIBA 05/2017 - 02/2012
2	Transcription Factors (Transcription Factor)IBA 01/2016 - 02/2008
2	Galectin 4 (LGALS4)IBA 04/2012 - 07/2010
2	AcidsIBA 12/2010 - 06/2010
2	GastrinsIBA 02/2006 - 08/2005
1	Immune Checkpoint InhibitorsIBA 04/2024
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 10/2023
1	pyrvinium (Vankin)FDA Link 10/2023
1	CholesterolIBA 01/2023
1	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 01/2023
1	Formaldehyde (Formol)FDA Link 10/2022

Therapy/Procedure

113	Gastrectomy 02/2024 - 04/2003
17	Lymph Node Excision (Lymph Node Dissection) 01/2022 - 12/2004
13	Drug Therapy (Chemotherapy) 04/2024 - 07/2009
7	Bariatric Surgery 12/2023 - 07/2017
6	Length of Stay 12/2023 - 08/2010
5	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/2023 - 07/2017
5	Therapeutics 09/2021 - 03/2010
3	Operative Time 12/2023 - 02/2011
3	Stents 01/2023 - 01/2015
3	Adjuvant Chemotherapy 07/2022 - 06/2013
3	Splenectomy 12/2017 - 10/2016
3	Minimally Invasive Surgical Procedures 03/2014 - 12/2004
2	Immunotherapy 04/2024 - 12/2007
2	Gastroenterostomy 12/2023 - 06/2008
2	Liver Transplantation 02/2023 - 09/2004
2	Aftercare (After-Treatment) 10/2021 - 01/2015
2	Operative Surgical Procedures 10/2011 - 06/2011
1	Obesity Management 01/2024
1	Patient-Controlled Analgesia (Analgesia, Patient Controlled) 01/2022